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Clinical Information​Stroke Prevention in Atrial Fibrillation​Morbidity and Mortality​Efficacy​Aristophanes​Safety​Real-world Data​Guideline recommendations​Persistence and Adherence​Dosing​Summary​Venous Thromboembolism TreatmentEfficacySafety​Real-world Data​Guideline recommendationsDosing​Venous Thromboembolism PreventionEfficacy​Safety​Dosing​Eliquis Important Safety InformationEliquis Abbreviated Prescribing Information (2.5 mg)​Eliquis Abbreviated Prescribing Information (5 mg) Support & Services​ Support & Services​ Self-detail presentations​ Webinars​ MaterialsVideos​
Morbidity and MortalityAF is associated with significant rate of morbidity and mortality3MORBIDITY

Adapted from Wolf P.et al. Stroke. 1991.

MORTALITY

Example

Adapted from Marini C.et al. Stroke. 2005.

AF: atrial fibrillation; NVAF: nonvalvular atrial fibrillation; VTE: venous thromboembolism.

References: 1. Eliquis 2.5 mg/ 5 mg Egyptian Drug Authority approved leaflet 17/08/2022. Revision Date: February 2022. 2. Granger CB, Alexander JH, McMurray JJ, et al. Apixaban versus warfarin in patients with atrial fibrillation. N Engl J Med. 2011;365(11):981-992. 3. Taggar J, Marin F, Lip G. Mortality in patients with atrial fibrillation: improving or not?. EP Europace. 2008;10(4):389-390
4. Wolf PA, Abbott RD, Kannel WB. Atrial fibrillation as an independent risk factor for stroke: the Framingham Study. Stroke. 1991;22(8):983-988. 5. Marini C, De Santis F, Sacco S, et al. Contribution of atrial fibrillation to incidence and outcome of ischemic stroke: results from a population-based study. Stroke. 2005;36(6):1115-1119. 6. Steinberg BA. How I use anticoagulation in atrial fibrillation. Blood. 2016;128(25):2891-2898. 7. Dulli DA, Stanko H, Levine RL. Atrial fibrillation is associated with severe acute ischemic stroke. Neuroepidemiology. 2003;22(2):118-123.

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HF0098OA451/122022​
Invalidation Date : 21/08/2024​
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SPAF Guideline recommendations
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